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Table 1 Characteristics of the study population

From: Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus

 

Cases (n = 411)

Controls (n = 511)

Combined (n = 922)

Mean age

43.54 ± 11.36

45.68 ± 12.86

44.68 ± 12.22

Body mass index (kg/m2)

26.90 ± 6.82

27.34 ± 6.59

27.14 ± 6.70

Current and/or Former Smoker (%)

37.84%

40.29%

39.23%

PON activity (in units/liter)*

613.88 ± 412.94

709.85 ± 496.39

671.44 ± 466.87

SLE manifestations (%)**

   

   Skin rash (malar and/or discoid)

55%

-

-

   Photosensitivity

63%

-

-

   Oral ulcers

54%

-

-

   Serositis (pleuritis or pericarditis)

44%

-

-

   Renal involvement

30%

-

-

   Hematologic involvement***

54%

-

-

   Immunologic involvement****

72%

-

-

   Cardiac and vascular events*****

33%

-

-

  1. *Available only in a subset of the sample (291 cases and 436 controls)
  2. ** The subset of American College of Rheumatology (ACR) classification criteria for SLE that were included in association analysis
  3. *** Hemolytic anemia or leukopenia (on two or more occasions) or lymphopenia (on two or more occasions) or thrombocytopenia
  4. **** Anti-DNA antibody or anti-Sm antibody or positive finding of antiphospholipid antibodies
  5. *****Data available only in a subset of SLE patients (292 cases)
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BMC Medical Genetics

ISSN: 1471-2350

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