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Table 2 Association between rs3761847 and rs7021206 in TRAF1/C5 and RA in a Han Chinese cohort

From: Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population

SNP

Phenotype

HWE

Genotype count (frequency)

Allele frequency

Allelic p

Adjusted p

OR (95%CI)

 

Case (576)

0.93

AA: 192 (0.33)

A:0.58

0.0018

0.0054

1.28 (1.10-1.50)

   

AG: 282 (0.49)

G:0.42

   

rs3761847

  

GG: 102 (0.18)

    
 

Control (689)

0.06

AA: 171 ( 0.25)

A:0.52

   
   

AG: 369 ( 0.54)

G:0.48

   
   

GG:149 ( 0.21)

    
 

Case (576)

0.07

AA: 239 (0.41)

A:0.66

0.005

0.015

1.27 (1.07-1.50)

   

AG: 279 (0.48)

G:0.34

   

rs7021206

  

GG: 58 (0.11)

    
 

Control (689)

0.54

AA: 343 (0.50 )

A:0.71

   
   

AG: 291 (0.42 )

G:0.29

   
   

GG: 55 ( 0.08 )

    
  1. SNP: single nucleotide polymorphism, HWE: Hardy-Weinberg equilibrium, OR: odds ratio, CI: confidence interval.
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BMC Medical Genetics

ISSN: 1471-2350

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