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Table 3 Significant associations between ADIPOQ SNPs and baseline body weight

From: Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study

    

pa/q

pb/q

rs266729 (N)

CC (219)c

CG, GG (288)d

   

All

85.04 (83.33-86.79)

87.66 (86.09-89.25)

 

0.025/0.024

0.020/0.700

male

91.36 (88.60-94.21)

89.69 (87.26-92.19)

 

0.385/0.420

 

female

80.18 (78.16-82.25)

84.46 (82.63-86.33)

 

0.003/0.036

 

rs16861205 (N)

GG (337)

GA (151)

AA (19)

  

All

87.66 (86.20-89.14)

84.37 (82.33-86.46)

83.86 (78.36-89.67)

0.023/0.024

0.528/0.684

 

GG (337)

AA, AG (170)

   

All

87.65 (86.20-89.13)

84.31 (82.39-86.26)

 

0.006/0.024

0.302/0.684

rs1501299 (N)

GG (234)

GT (220)

TT (53)

  

All

88.09 (86.37-89.84)

85.36 (83.63-87.13)

84.16 (80.80-87.66)

0.032/0.024

0.486/0.684

 

GG (234)

GT, TT (273)

   

All

88.09 (86.37-89.84)

85.13 (83.56-86.72)

 

0.011/0.024

0.407/0.684

rs3821799 (N)

CC (149)

CT (255)

TT (103)

  

All

89.63 (87.49-91.82)

85.64 (84.02-87.29)

83.99 (81.56-86.48)

0.001/0.024

0.187/0.700

 

CC (149)

CT, TT (358)

   

All

89.63 (87.49-91.82)

85.16 (83.78-86.57)

 

0.0005/0.024

0.072/0.724

 

CC, CT (404)

TT (103)

   

All

87.13 (85.80-88.48)

84.03 (81.59-86.55)

 

0.029/0.024

0.861/0.684

rs6773957 (N)

GG (206)

GA (233)

AA (68)

  

All

88.31 (86.49-90.17)

85.29 (83.61-87.01)

84.98 (81.95-88.12)

0.033/0.024

0.200/0.700

 

GG (206)

AA, AG (301)

   

All

88.31 (86.50-90.17)

85.22 (83.72-86.76)

 

0.009/0.024

0.172/0.684

  1. Data are expressed as retransformed geometric mean (95% CI)
  2. Correction for multiple hypothesis testing was performed with FDR, denoted as q-value.
  3. a adjusted for age and sex
  4. b p for sex-genotype interaction
  5. c Men: N = 74, Women N = 145
  6. d Men: N = 92, Women N = 196
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BMC Medical Genetics

ISSN: 1471-2350

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