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Table 3 Genotype and Allelic Frequencies of PTTG1 htSNPs among Pituitary Adenoma Cases and Controls and Associations with Risk of Pituitary Adenoma

From: Pituitary tumor transforming gene-1 haplotypes and risk of pituitary adenoma: a case-control study

 

Cases/Controls

OR (95% CI)

P

rs1895320

   

Genotype

   

CC

2/4

0.46 (0.08-2.57)

0.68a

CT

84/88

0.91 (0.64-1.31)

0.67b

TT

194/188

1.00

0.45c

Allele

   

C

88/96

0.90 (0.66-1.24)

 

T

472/464

1.00

0.52*

rs2910200

   

Genotype

   

TT

4/4

1.12 (0.27-4.58)

0.73d

TC

72/54

1.48 (0.99-2.22)

0.06e

CC

202/222

1.00

1.00f

Allele

   

T

80/62

1.35 (0.95-1.93)

 

C

476/498

1

0.10*

rs6882742

   

Genotype

   

CC

4/10

0.36 (0.11-1.16)

0.27g

CT

90/104

0.80 (0.56-1.14)

0.26h

TT

176/166

1.00

0.11i

Allele

   

C

98/124

0.78 (0.58-1.05)

 

T

442/436

1.00

0.10*

  1. Note: As certain genotypes have expected count less than 5 in cases or controls, separate Fisher's exact tests and Chi-square tests are performed where appropriate. a, Fisher's exact P value for rs1895320 CC vs. CT; b, Chi-square P value for rs1895320 CT vs. TT; c, Fisher's exact P value for rs1895320 CC vs. TT; d, Fisher's exact P value for rs2910200 TT vs. TC; e, Chi-square P value for rs2910200 TC vs. CC; f, Fisher's exact P value for rs2910200 TT vs. CC; g, Fisher's exact P value for rs6882742 CC vs. CT; h, Chi-square P value for rs6882742 CT vs. TT; i, Fisher's exact P value for rs6882742 CC vs. TT; *Chi-square P value.
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BMC Medical Genetics

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