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Figure 2 | BMC Medical Genetics

Figure 2

From: Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease

Figure 2

Simulated effects of statin use on the odds ratio for CHD in KIF6 719Arg carriers vs. noncarriers. Results are presented where KIF6 719Arg carriers have 50% or 25% increased risk of CHD compared with noncarriers if there is no statin use, and 0% increased risk of CHD compared with noncarriers if statins are used. Odds ratios (vertical axis) are presented for increasing percentage of statin use (horizontal axis).

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