Table 2 Fasting serum lipid levels of successfully genotyped normoglycemic and hyperglycemic Danes from the Inter99 cohort stratified according to ACADS rs2014355 genotype
WT | HE | HO | β (95% CI) | P add | |
|---|---|---|---|---|---|
Normoglycemic | |||||
n (men/women) | 2576(1208/1368) | 1496(694/802) | 252(105/147) | ||
Age (years) | 45.2 ± 7.8 | 45.4 ± 7.9 | 44.9 ± 7.9 | ||
Lipid characteristics (mmol/l) | |||||
Total serum cholesterol | 5.4 ± 1.0 | 5.4 ± 1.0 | 5.4 ± 1.1 | 0.001 (-0.046; 0.048) | 0.97 |
HDL-cholesterol | 1.5 ± 0.4 | 1.5 ± 0.4 | 1.5 ± 0.4 | 0.002 (-0.016; 0.019) | 0.86 |
LDL-cholesterol | 3.5 ± 1.0 | 3.5 ± 1.0 | 3.5 ± 1.0 | -0.001 (-0.065; 0.063) | 0.97 |
VLDL-cholesterol | 0.5 ± 0.3 | 0.6 ± 0.3 | 0.5 ± 0.2 | 0.007 (-0.012; 0.026) | 0.46 |
Serum triglyceride | 1.0 (0.7-1.4) | 1.0 (0.7-1.4) | 1.0 (0.7-1.3) | 0.5% (-1.8%; 2.7%) | 0.69 |
Hyperglycemic | |||||
n (men/women) | 804(473/331) | 496(306/190) | 78(49/29) | ||
Age (years) | 48.8 ± 7.4 | 49.4 ± 7 | 47.8 ± 8.1 | ||
Lipid characteristics (mmol/l) | |||||
Total serum cholesterol | 5.8 ± 1.1 | 5.9 ± 1.2 | 5.9 ± 1.2 | 0.09 (-0.01;0.19) | 0.08 |
HDL-cholesterol | 1.4 ± 0.4 | 1.3 ± 0.4 | 1.3 ± 0.5 | -0.036 (-0.067; -0.005) | 0.02 |
LDL-cholesterol | 3.7 ± 1.0 | 3.7 ± 1.0 | 3.9 ± 1.4 | 0.06 (-0.07; 0.19) | 0.38 |
VLDL-cholesterol | 0.7 ± 0.4 | 0.7 ± 0.4 | 0.8 ± 0.4 | 0.03 (-0.02; 0.08) | 0.21 |
Serum triglyceride | 1.4 (0.9-2.0) | 1.4 (1.1-2.0) | 1.5 (1.1-2.6) | 5.2% (0.4%; 10.0%) | 0.03 |