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Table 4 Odds ratio (OR) and 95% confidence interval (95% CI) of low serum uric acid (SUA) for SLC22A12 W258X among Japanese health checkup examinees

From: Serum uric acid distribution according to SLC22A12 W258X genotype in a cross-sectional study of a general Japanese population

 

SUA < 3 mg/dL

SUA < 4 mg/dL

Genotype

< 3 mg/dL

3 mg/dL ≤

OR

95% CI

< 4 mg/dL

4 mg/dL ≤

OR

95% CI

Males

        

   WW

4

3,252

1

Reference

55

3,201

1

Reference

   WX or XX

17

140

102.5

33.9-309.8

79

78

58.2

38.6-87.9

   Total

21

3,392

  

157

3,279

  

Females

        

   WW

53

1,484

1

Reference

436

1,101

1

Reference

   WX or XX

31

42

25.6

14.4-45.3

58

15

11.9

6.6-21.5

   Total

84

1,526

  

494

1,116

  

Both sexes

        

   Males with WW

4

3,252

1

Reference

55

3,201

1

Reference

   Males with WX or XX

17

140

106.5

35.3-321.6

79

78

63.7

42.0-96.5

   Females with WW

53

1,484

27.2

9.8-75.4

436

1,101

22.4

16.8-29.9

   Females with WX or XX

31

42

672.6

225.4-2006.8

58

15

246.3

130.9-363.7

   Interaction*

  

0.23

0.07-0.80

  

0.17

0.08-0.35

   Total

105

4,918

  

628

4,395

  
  1. * Interaction between females and X allele for low SUA.