Table 1 Genotype distribution of the RET gene polymorphisms in case-control

-5G > A, rs10900296 ^a

GG

50 (29.8)

7 (5.7)

Reference

GA

83 (49.4)

29 (23.9)

2.50 (1.02-6.12); 0.046

AA

35 (20.8)

87 (67.4)

17.75 (7.34-42.92); < 0.001

-1A > C, rs10900297 ^b

AA

22 (13.1)

3 (2.4)

Reference

AC

80 (47.6)

22 (17.9)

2.02 (0.55-7.38); 0.288

CC

66 (39.3)

98 (79.7)

10.89 (3.13-37.85); < 0.001

c135G > A, rs1800858 ^c

GG

52 (31.0)

10 (8.1)

Reference

GA

85 (50.6)

32 (26.0)

1.95 (0.89-4.32); 0.095

AA

31 (18.4)

81 (65.9)

13.61 (6.14-30.14); < 0.001

C1296A > G, rs1800860 d

AA

6 (3.6)

0 (0.0)

Reference

AG

54 (32.1)

23 (18.7)

GG

108 (64.3)

100 (81.3)

2.40 (1.38-4.18); 0.002

c2307T > G, rs1800861 ^e

TT

37 (22.0)

9 (7.3)

Reference

TG

95 (56.6)

26 (21.1)

1.08 (0.46-2.53); 0.853

GG

36 (21.4)

88 (71.6)

9.79 (4.28-22.43); < 0.001