Table 3 Effect of rs7903146 genotype on sulfonylurea treatment failure under logistic regression analysis.
From: TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
Genotype rs7903146 | Total | Controls (A1C <7%) | Failure of treatment with sulfonylurea (A1C≥7%) | Frequency of T-allele (controls vs. treatment failure) | Additive P value OR (95% CI) |
|---|---|---|---|---|---|
n = 188 | n = 91 | n = 97 | |||
CC | 91 (48.4%) | 51 (56.0%) | 40 (41.2%) | ||
CT | 78 (41.5%) | 33 (36.3%) | 45 (46.4%) | 0.26/0.36 | 0.046 1.57 (1.01-2.45) |
TT | 19 (10.1%) | 7 (7.7%) | 12 (12.4%) |