Table 2 Univariate regression analyses of predictors on failure of sulfonylurea treatment in patients with type 2 diabetes.
From: TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
Odds ratio (95% CI) | P-value | |
|---|---|---|
Gender | 0.98 (0.56-1.74) | 0.95 |
Age (yr) | 1.00 (0.97-1.03) | 0.98 |
Diabetes duration (<5 yrs vs. >5 yrs) | 1.65 (0.86-3.17) | 0.13 |
Sulfonylurea daily dose (mg) | 1.01 (0.97-1.06) | 0.57 |
TCF7L2 genotype (rs7903146; per allele effect) | 1.57 (1.01-2.45) | 0.046 |
TCF7L2 genotype (CC vs. TT) | 2.09 (1.02-4.27) | 0.043 |