Figure 4
From: Variable expressivity of FGF3 mutations associated with deafness and LAMM syndrome
A homology model of FGF3 generated using the structure of FGF10 (1NUN.PDB) as a template and the SWISS-MODEL server. FGF3 was then docked on the structure of FGFR2b in a manner identical to that of FGF10 in the FGF10-FGFR2b complex. FGFR2b is represented by the tan cartoon, while FGF3 is shown as a ribbon color coded from the N- to the C-terminus in blue to red. The residues Gly 66, Arg 95 and Ser 156 are shown as spheres. The image was generated using PYMOL [25].