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Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) for doctor-diagnosed allergic rhinitis according to IL13 polymorphisms in Japanese women, KOMCHS, Japan

From: Case-control study of IL13 polymorphisms, smoking, and rhinoconjunctivitis in Japanese women: the Kyushu Okinawa Maternal and Child Health Study

SNP

Genotype

Cases n(%)

Controls n(%)

Crude OR (95% CI)

Adjusted OR (95% CI)*

rs1800925

 

(N = 293)

(N = 767)

  

   Model 1

CC

201 (68.6)

516 (67.3)

1.00

1.00

 

CT

84 (28.7)

230 (30.0)

0.94 (0.70 - 1.26)

0.97 (0.71 - 1.33)

 

TT

8 (2.7)

21 (2.7)

0.98 (0.43 - 2.24)

0.89 (0.38 - 2.13)

   Model 2

CC

201 (68.6)

516 (67.3)

1.00

1.00

 

CT + TT

92 (31.4)

251 (32.7)

0.94 (0.70 - 1.26)

0.96 (0.71 - 1.30)

rs20541

 

(N = 293)

(N = 766)

  

   Model 1

GG

135 (46.1)

379 (49.5)

1.00

1.00

 

GA

126 (43.0)

333 (43.5)

1.06 (0.80 - 1.41)

1.08 (0.80 - 1.46)

 

AA

32 (10.9)

54 (7.1)

1.66 (1.03 - 2.69)

1.66 (1.004 - 2.75)

   Model 2

GG

135 (46.1)

379 (49.5)

1.00

1.00

 

GA + AA

158 (53.9)

387 (50.5)

1.15 (0.88 - 1.50)

1.16 (0.88 - 1.55)

  1. * Adjusted for age, region of residence, presence of older siblings, smoking, family history of allergic rhinitis, and education.