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Table 2 Odds ratios (OR) for the 11 SNPs for the Baltic, Danish and Norwegian UC panels1

From: Assessment of heterogeneity between European Populations: a Baltic and Danish replication case-control study of SNPs from a recent European ulcerative colitis genome wide association study

  

Baltic1

441 UC cases/1156 controls

Danish

560 UC cases/796 controls

Norwegian1

274 UC cases/282 controls

European1

3989 co/1822 ca

SNP

A1

FCA

FCO

OR

95% CI

PCCA

FCA

FCO

OR

95% CI

PCCA

FCA

FCO

OR

95% CI

PCCA

FCA

rs7520292

A

0.20

0.20

1.04

0.85-1.25

0.71

0.17

0.16

1.01

0.81-1.24

0.94

0.16

0.16

1.00

0.73-1.38

0.96

0.20

rs1488266 BTLA

C

0.06

0.06

0.95

0.69-1.29

0.72

0.10

0.11

0.91

0.71-1.16

0.45

0.09

0.10

0.90

0.60-1.36

0.64

0.10

rs3103190

G

0.40

0.41

0.98

0.83-1.14

0.76

0.30

0.33

0.87

0.73-1.02

0.09

0.31

0.31

0.99

0.77-1.27

0.95

0.34

rs12518307

A

0.33

0.33

1.00

0.84-1.17

0.99

0.27

0.23

1.19

1.00-1.42

0.04

0.27

0.26

1.04

0.79-1.35

0.77

0.25

rs2395609 TCP11

G

0.29

0.30

0.92

0.77-1.09

0.35

0.34

0.33

1.04

0.88-1.23

0.60

0.35

0.36

0.97

0.76-1.24

0.83

0.32

rs7809799 SMURF1/KPNA71

G

0.07

0.05

1.42

1.03-1.94

0.03

0.03

0.04

0.86

0.57-1.27

0.44

0.04

0.02

1.6

0.86-3.23

0.11

0.05

rs6966125 TNP03

G

0.21

0.20

1.01

0.83-1.22

0.89

0.15

0.14

1.10

0.88-1.36

0.40

0.12

0.14

0.84

0.59-1.19

0.33

0.16

rs638300

T

0.15

0.14

1.09

0.88-1.35

0.42

0.20

0.20

0.97

0.80-1.17

0.77

0.21

0.19

1.10

0.82-1.48

0.49

0.21

rs6119625 FER1L4

G

0.15

0.14

1.08

0.87-1.34

0.47

0.13

0.12

1.11

0.88-1.39

0.37

0.13

0.10

1.28

0.89-1.83

0.17

0.15

rs6125345

C

0.17

0.18

0.93

0.75-1.13

0.45

     

0.19

0.16

1.20

0.88-1.63

0.24

0.20

rs5771069 IL17REL

A

0.50

0.52

0.93

0.79-1.08

0.31

0.49

0.50

0.97

0.82-1.12

0.67

0.43

0.53

0.69

0.54-0.87

0.002

0.49

  1. 1Data for the 11 SNPs in the Norwegian panel, for rs5771069 and rs7809799 in the Baltic panel, and the allele frequencies for the combined German, British, Belgian, and Greek panel is from Franke et al [7].
  2. A1: minor allele; F: allele frequency of A1 for cases (FCA) or controls (FCO), respectively; 95%CI: 95% confidence interval; PCCA: P-value (Pearson's χ2 test on allele counts with one degree of freedom); nominal significant P-values are highlighted by bold type