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Table 3 Genotype and allele association analysis of 5 single nucleotide polymorphisms

From: Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population

SNP ID Polymorphisms Genotype/allele Patients with asthma, n (%) Controls, n (%) OR 95% CI P value P*
rs7216389 (GSDMB) TT 384 (55.2) 298 (46.8) 1    
  CT 258 (37.1) 286 (44.9) 1.43 1.14-1.80 0.008  
  CC 54 (7.7) 53 (8.3) 1.27 0.84-1.90   0.01
  T 1026 (73.7) 882 (69.2) 1   0.011  
  C 366 (26.3) 392 (30.8) 1.25 1.05-1.48   
rs12603332 (ORMDL3) CC 385 (54.2) 302 (46.04) 1    
  CT 268 (37.8) 300 (45.73) 1.43 1.14-1.784 0.007  
  TT 57 (8.0) 54 (8.23) 1.21 0.81-1.81   0.01
  C 1038 (73.1) 904 (68.9) 1   0.016  
  T 382 (26.9) 408 (31.1) 1.23 1.04-1.45   
rs12936231 (ZPBP2) CC 393 (56.1) 298 (47.8) 1    
  CG 257 (36.7) 278 (44.6) 1.43 1.14-1.79 0.009  
  GG 50 (7.1) 47 (7.5) 1.24 0.81-1.90   0.01
  C 1043 (74.5) 874 (70.0) 1   0.013  
  G 357 (25.5) 372 (30.0) 1.24 1.05-1.48   
rs11557467 (ZPBP2) GG 383 (55.51) 300 (46.80) 1    
  GT 257 (37.25) 288 (44.93) 1.43 1.14-1.79 0.006  
  TT 50 (7.25) 53 (8.27) 1.35 0.89-2.05   0.005
  G 1023 (74.13) 888 (69.27) 1   0.006  
  T 357 (25.87) 394 (30.73) 1.27 1.07-1.51   
rs9303277 (IKZF3) CC 348 (50.58) 269 (42.43) 1    
  CT 278 (40.41) 295 (46.53) 1.37 1.09-1.73 0.012  
  TT 62 (9.01) 70 (11.04) 1.46 1.00-2.13   0.004
  C 974 (70.78) 833 (65.69) 1   0.005  
  T 402 (29.22) 435 (34.31) 1.27 1.07-1.49   
  1. SNP, single nucleotide polymorphism; OR, odds ratio; 95% CI, 95% confidence interval; P* adjusted for age and sex