Skip to main content

Table 1 Frequency of CYBA - 657 T → A (unregistered), GCLC - 129 C → T (rs17883901) and GPX3 - 65 T → C (rs8177412) polymorphisms in type 1 diabetes patients and non-diabetic control subjects.

From: Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic subunit (GCLC) and renal disease in patients with type 1 diabetes mellitus

 

Non-diabetic control subjects

n = 118

Type 1 diabetes patients

n = 401

Sex (male/female)

44.2%/54.8%

49.5%/50.5%

Age (years)*

36 (29-44.5)

34.7 (27.8-43)

- 675 T → A CYBA genotypes

  

   T/T

101 (85.6%)

351 (87.5%)

   T/A

17 (14.4%)

47 (11.7%)

   A/A

0 (0%)

3 (0.8%)

- 129 C → T GCLC genotypes

  

   C/C

97 (82.2%)

333 (83%)

   C/T

21 (17.8%)

64 (16%)

   T/T

0 (0%)

4 (1%)

- 65 T → C GPX3 genotypes

  

   T/T

87 (73.7%)

298 (74.3%)

   T/C

28 (23.8%)

98 (24.5%)

   C/C

3(2.5%)

5 (1.2%)

  1. *median ± interquartile interval.