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Table 3 Distribution of NOD1 and TLR4 gene polymorphisms in Helicobacter pylori positive and negative subjects

From: Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians

Genotypes

Hp negative

Hp positive

  
 

n (%)

n (%)

OR (95% CI)

p

NOD1 796G>A

    

G/G

133 (57.8)

195 (57.4)

0.98 (0.69-1.37)

0.910

G/A

75 (32.6)

116 (34.1)

1.07 (0.75-1.52)

0.708

A/A

22 (9.60)

29 (8.50)

0.88 (0.49-1.57)

0.670

Allele G

341 (74.1)

506 (74.4)

1.01 (0.77-1.33)

0.915

Allele A

119 (25.9)

174 (25.6)

0.98 (0.75-1.29)

0.915

TLR4 3725G>C

    

G/G

182 (79.1)

279 (82.3)

1.22 (0.80-1.87)

0.343

G/C

44 (19.1)

51 (15.0)

0.74 (0.48-1.16)

0.199

C/C

4 (1.8)

9 (2.7)

1.54 (0.46-5.06)

0.549

Allele G

408 (88.7)

609 (89.8)

1.12 (0.76-1.64)

0.545

Allele C

52 (11.3)

69 (10.2)

0.88 (0.60-1.30)

0.545

  1. Hp, Helicobacter pylori; OR, odds ratio
  2. The ORs were calculated comparing each genotype vs. the other two genotypes, the first line for each gene polymorphism represents the dominant model and third line represents the recessive model.
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BMC Medical Genetics

ISSN: 1471-2350

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