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Table 4 Association analysis of SNPs with quantitative traits in control subjects in the initial phase

From: No association of TNFRSF1B variants with type 2 diabetes in Indians of Indo-European origin

 

rs496888

 

rs6697733

 

rs945439

 

rs235249

 

rs17884213

 
 

Median (IQR)

P

Median (IQR)

P

Median (IQR)

P

Median (IQR)

P

Median (IQR)

P

Trait

AA/AG/GG

 

TT/TC/CC

 

TT/TC/CC

 

TT/TC/CC

 

GG/GA/AA

 

BMI

23.7 (20.4-27.0)

23.5 (20.0-26.6)

24.6 (22.4-29.0)

0.132

23.9 (20.5-26.9)

23.6 (20.2-26.9)

24.1 (20.2-27.6)

0.593

23.7 (20.4-26.7)

23.6 (20.3-27.0)

25.0 (21.8-28.0)

0.209

23.7 (20.4-26.9)

23.5 (20.3-26.9)

25.0 (21.7-27.8)

0.268

23.9 (20.4-27.2)

23.4 (20.3-26.4)

25.5 (21.6-28.2)

0.063

WHR

0.93 (0.87-0.98)

0.92 (0.86-0.98)

0.93 (0.87-0.98)

0.913

0.93 (0.87-0.98)

0.93 (0.87-0.99)

0.92 (0.86-0.97)

0.549

0.93 (0.87-0.98)

0.93 (0.86-0.99)

0.91 (0.87-0.97)

0.446

0.93 (0.87-0.98)

0.93 (0.86-0.99)

0.91 (0.87-0.97)

0.582

0.93 (0.86-0.98)

0.93 (0.87-0.99)

0.93 (0.87-0.97)

0.568

HbA1c

5.2 (4.9-5.6)

5.2 (4.9-5.6)

5.2 (4.9-5.3)

0.358

5.3 (4.9-5.6)

5.2 (4.9-5.5)

5.2 (4.8-5.5)

0.174

5.3 (4.9-5.6)

5.2 (4.9-5.5)

5.2 (4.8-5.5)

0.247

5.3 (4.9-5.6)

5.2 (4.5-5.5)

5.3 (4.9-5.5)

0.472

5.3 (4.9-5.6)

5.2 (4.9-5.6)

5.1 (4.9-5.5)

0.194

FPG

4.9 (4.5-5.3)

4.9 (4.5-5.2)

5.0 (4.3-5.3)

0.425

5.0 (4.5-5.3)

4.9 (4.5-5.2)

4.9 (4.5-5.2)

0.348

4.9 (4.5-5.3)

4.9 (4.5-5.2)

4.9 (4.5-5.2)

0.315

4.9 (4.5-5.3)

4.9 (4.5-5.2)

5.0 (4.6-5.2)

0.275

4.9 (4.5-5.3)

4.9 (4.5-5.2)

5.0 (4.6-5.2)

0.236

FPI

32.4 (16.8-56.4)

31.8 (18.6-60.0)

36.0 (21.0-67.2)

0.543

33.6 (17.4-61.2)

31.8 (18.0-54.0)

26.4 (16.2-43.2)

0.279

33.6 (17.4-60.6)

31.8 (18.6-54.0)

24.6 (15.6-41.4)

0.190

32.4 (16.8-59.4)

31.2 (18.6-54.0)

30.6 (15.6-51.0)

0.890

34.2 (18.0-59.4)

30.6 (17.4-54.0)

30.6 (17.4-44.4)

0.536

HOMA-IR

1.2 (0.6-2.0)

1.1 (0.6-2.0)

1.1 (0.7-2.4)

0.717

1.2 (0.6-2.2)

1.2 (0.6-1.9)

1.0 (0.6-1.5)

0.227

1.2 (0.6-2.2)

1.2 (0.6-1.9)

0.9 (0.5-1.4)

0.200

1.1 (0.6-2.1)

1.2 (0.6-1.9)

1.1 (0.6-1.9)

0.896

1.2 (0.6-2.2)

1.1 (0.6-1.9)

1.1 (0.6-1.5)

0.553

C-peptide

0.53 (0.36-0.73)

0.53 (0.40-0.76)

0.60 (0.43-0.79)

0.445

0.53 (0.40-0.76)

0.53 (0.36-0.73)

0.50 (0.33-0.63)

0.278

0.53 (0.40-0.76)

0.53 (0.36-0.73)

0.50 (0.33-0.60)

0.158

0.53 (0.40-0.76)

0.53 (0.36-0.76)

0.50 (0.33-0.63)

0.596

0.53 (0.40-0.76)

0.53 (0.36-0.73)

0.50 (0.40-0.66)

0.716

CRP

1.25 (0.59-2.67)

1.11 (0.58-2.57)

0.77 (0.37-1.64)

0.042

1.20 (0.58-2.48)

1.14 (0.58-2.86)

1.13 (0.66-2.78)

0.860

1.21 (0.57-2.52)

1.13 (0.59-2.87)

1.13 (0.70-2.54)

0.855

1.19 (0.55-2.48)

1.16 (0.60-2.93)

1.14 (0.75-2.84)

0.894

1.28 (0.57-2.70)

1.07 (0.57-2.43)

1.21 (0.71-3.35)

0.212

TC

4.42 (3.80-5.17)

4.42 (3.78-5.09)

4.14 (3.70-4.86)

0.408

4.42 (3.83-5.15)

4.37 (3.75-5.12)

4.34 (3.72-5.04)

0.605

4.4 (3.80-5.17)

4.37 (3.72-5.09)

4.42 (3.93-5.20)

0.532

4.4 (3.78-5.15)

4.4 (3.75-5.12)

4.4 (3.90-5.09)

0.986

4.40 (3.78-5.15)

4.42 (3.80-5.12)

4.27 (3.85-4.84)

0.636

HDL-C

1.06 (0.88-1.29)

1.06 (0.91-1.29)

1.09 (0.93-1.19)

0.857

1.06 (0.91-1.29)

1.06 (0.88-1.29)

1.11 (0.85-1.34)

0.947

1.06 (0.91-1.29)

1.06 (0.88-1.29)

1.09 (0.88-1.27)

0.899

1.06 (0.88-1.29)

1.06 (0.88-1.29)

1.06 (0.88-1.27)

0.938

1.06 (0.91-1.29)

1.09 (0.88-1.29)

1.03 (0.85-1.22)

0.637

LDL-C

2.82 (2.35-3.44)

2.79 (2.35-3.36)

2.66 (2.17-3.41)

0.775

2.82 (2.38-3.47)

2.74 (2.25-3.39)

2.77 (2.43-3.44)

0.338

2.82 (2.35-3.47)

2.74 (2.25-3.39)

2.74 (2.51-3.44)

0.293

2.82 (2.35-3.47)

2.79 (2.30-3.41)

2.74 (2.48-3.31)

0.814

2.79 (2.35-3.41)

2.84 (2.33-3.41)

2.64 (2.28-3.26)

0.699

TG

1.32 (0.98-1.84)

1.34 (0.98-1.83)

1.33 (1.05-1.77)

0.951

1.33 (0.98-1.86)

1.31 (0.96-1.76)

1.38 (1.11-1.73)

0.562

1.32 (0.97-1.9)

1.31 (0.97-1.74)

1.36 (1.11-1.73)

0.578

1.32 (0.96-1.86)

1.37 (1.01-1.76)

1.36 (1.11-1.81)

0.839

1.32 (0.96-1.86)

1.31 (0.99-1.77)

1.43 (1.06-1.75)

0.940

  1. IQR: interquartile range. The P values were obtained by performing Kruskal-Wallis test.