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Table 1 Anthropometric and clinical characteristics of the study populations

From: No association of TNFRSF1B variants with type 2 diabetes in Indians of Indo-European origin

 

Initial phase

 

Replication phase

 

Characteristics

Type 2 diabetes patients

Control

Subjects

Type 2 diabetes patients

Control

subjects

N (Men/Women)

1019 (592/427)

1006 (606/400)

1047 (619/428)

1038 (516/522)

Age (years)

53 (45-62)

50 (44-60)

55 (49-62)

54 (45-64)

BMI (Kg/m2)

    

   Men

23.8 (22.0-26.0)

23.1 (20.1-25.7)

24.8 (22.7-27.8)

24.7 (22.3-27.4)

   Women

26.7 (24.2-29.2)

25.0 (21.1-28.5)

27.4 (24.6-30.6)

26.4 (23.1-29.3)

WHR

    

   Men

1.00 (0.97-1.03)

0.97 (0.92-1.0)

0.98 (0.95-1.03)

0.97 (0.93-1.01)

   Women

1.00 (0.97-1.03)

0.86 (0.82-0.92)

0.93 (0.87-0.97)

0.86 (0.82-0.90)

Systolic BP (mmHg)

130 (130-140)

120 (112-132)

130 (122-140)

130 (120-140)

Diastolic BP (mmHg)

80 (78-90)

80 (70-88)

82 (80-90)

80 (78-90)

HbA1c (%)

7.8 (6.5-9.4)

5.2 (4.9-5.6)

8.2 (6.9-9.6)

5.6 (5.3-5.9)

FPG (mmol/L)

7.9 (6.4-10.3)

4.9 (4.5-5.3)

7.8 (6.2-10.3)

4.9 (4.4-5.3)

FPI (pmol/L)

82.8 (42.0-166.8)

32.4 (17.4-57.6)

74.4 (26.0-96.0)

43.8 (28.2-63.6)

HOMA-IR

5.20 (2.30-9.60)

1.20 (0.60-2.00)

4.30 (2.30-9.30)

1.60 (1.00-2.40)

C-peptide (nmol/L)

0.89 (0.56-1.36)

0.53 (0.36-0.73)

1.05 (0.69-1.60)

0.66 (0.50-0.86)

hsCRP (mg/L)

2.20 (0.90-4.70)

1.30 (0.60-3.00)

1.86 (0.90-3.44)

1.61 (0.90-3.04)

TC (mmol/L)

4.20 (3.50-5.00)

4.40 (3.7-5.10)

4.64 (3.86-5.42)

4.91 (4.22-5.52)

LDL-C (mmol/L)

2.57 (1.99-3.36)

2.79 (2.33-3.41)

2.73 (2.10-3.42)

3.01 (2.49-3.51)

HDL-C (mmol/L)

1.03 (0.88-1.22)

1.06 (0.88-1.28)

1.11 (0.94-1.34)

1.24 (1.06-1.46)

TG (mmol/L)

1.60 (1.10-2.20)

1.30 (1.00-1.80)

1.43 (0.98-2.13)

1.22 (0.86-1.64)

  1. Data are median values with interquartile ranges in parentheses. WHR: waist-hip ratio; FPG: fasting plasma glucose; FPI: fasting plasma insulin; HOMA-IR: homeostasis model assessment of insulin resistance; TC: total cholesterol; TG: triglyceride