| | | | | | |
Co-dominant
|
Dominant
|
Recessive
|
---|
Population
|
sample size
|
male
|
female
|
mean age*
|
mean_BMI* (kg/m2)
|
risk allele frequency
|
effect estimate (kg/m2)#
|
P
|
effect estimate (kg/m2)#
|
P
|
effect estimate (kg/m2)#
|
P
|
---|
Maori
|
110
|
32
|
78
|
48.1 ± 17.7
|
32.1 ± 7.6
|
0.833
|
0.024 ± 1.41
|
0.99
|
0.146 ± 1.60
|
0.93
|
-0.907 ± 4.52
|
0.84
|
Tongans
|
184
|
63
|
121
|
46.3 ± 14.0
|
34.0 ± 6.3
|
0.592
|
1.397 ± 0.66
|
0.037
|
2.341 ± 0.95
|
0.014
|
0.940 ± 1.26
|
0.46
|
All
|
294
|
95
|
199
|
47.0 ± 15.5
|
33.3 ± 6.9
|
0.686
|
0.351 ± 0.60
|
0.56
|
0.735 ± 0.81
|
0.366
|
-0.248 ± 1.29
|
0.85
|
- * Standard deviation is shown.
-
# Standard error is shown.
- The linear regression model used to produce effect estimates included age and sex as covariates. In the analysis including all populations, "population" was also included as a covariate. Results for all three modes of inheritance (co-dominant, dominant and recessive) are shown. Statistically significant P values (P < 0.05) are shown in bold.