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Table 3 Multiple logistic regression analysis of the association of the G319S carrier status in HNF1A with the incidence of type 2 diabetes

From: HNF1AG319S variant, active cigarette smoking and incident type 2 diabetes in Aboriginal Canadians: a population-based epidemiological study

Covariate adjustment

OR (95% CI)

p

Model 1: age + sex

3.24 (1.90-5.53)

< 0.0001

Model 2: model 1 + hypertension + triglyceride + HDL cholesterol + waist circumference

3.78 (2.13-6.69)

< 0.0001

Model 3: model 2 + fasting glucose

3.93 (2.20-7.03)

< 0.0001

Model 4: model 3 + HOMA-insulin resistance

3.83 (2.13-6.89)

< 0.0001

  1. Abbreviation: OR, odds ratio; CI, confidence interval; HOMA, homoeostasis model assessment. OR and 95% CI per 1-unit change (G319/G319, S319/G319 and S319/S319 corded as 0, 1, and 1).