From: LINE-1 methylation is inherited in familial testicular cancer kindreds
Variables | No. (%) | Mean level* | 95% CI | P |
---|---|---|---|---|
Family, healthy | 255 (54.7) | 79.31 | 79.06-79.56 | Â |
Family, other cancer | 39 (8.4) | 79.11 | 78.47-79.74 | Â |
Family, other condition§ | 20 (4.3) | 79.71 | 78.84-80.58 |  |
TGCT patients | 152 (32.6) | 79.13 | 78.78-79.45 | 0.377¶ |
   Multi-case families | 118 (77.6) | 79.50 | 79.12-79.88 |  |
   Sporadic bilateral TGCT | 34 (22.4) | 78.91 | 78.21-79.60 | 0.142¥ |
Gender‡ |  |  |  |  |
   Male | 114 (44.7) | 79.60 | 79.26-79.95 |  |
   Female | 141 (55.3) | 78.87 | 78.55-79.18 | 0.002 †|
Patient TGCT type | Â | Â | Â | Â |
   NOS | 4 (2.6) | 77.74 | 75.68-79.81 |  |
   Seminoma | 73 (48) | 79.19 | 78.70-79.68 |  |
   Non-seminoma | 75 (49.3) | 79.59 | 79.11-80.08 | 0.267a |
Choriocarcinoma | 2 (2.7) | 79.53 | 76.86-82.20 | Â |
Embryonal | 15 (20) | 79.88 | 78.90-80.86 | Â |
Germinoma | 2 (2.7) | 78.58 | 75.91-81.26 | Â |
Mixed germ cell | 34 (45.3) | 79.19 | 78.52-79.86 | Â |
Teratocarcinoma | 20 (26.7) | 80.78 | 79.84-81.73 | Â |
Yolk sac tumor | 2 (2.7) | 76.06 | 74.27-79.85 | Â |
Total participants | 466 | 79.25 | 79.08-79.43 | Â |