Figure 1From: Novel MLPA procedure using self-designed probes allows comprehensive analysis for CNVs of the genes involved in Hirschsprung disease MLPA profiles for control individuals (red) and for the HSCR patient (blue). Two different probes-mixes are shown (A and C mix 1; B and D mix 2). For those HSCR patients (A and B, HSCR-115; C and D, HSCR-5), it was observed a decrease for the dosage of GFRA1 exons 1, 2, 3 and 4, highlighted in red boxes and by arrows.Back to article page