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Table 7 MMP - 1 and 12 Risk Haplotypes related to disease GOLD severity III and IV combined versus controls

From: Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12in a European population

 

SNP No

P-value+

Haplotypes

6

10

12

13

14

16

18

 

2-SNP

    

x

 

x

0.0086

3-SNP

 

x

  

x

 

x

0.0116

3-SNP

   

x

x

 

x

0.0094

3-SNP

    

x

x

x

0.0076

4-SNP

x

  

x

x

 

x

0.0110

4-SNP

 

x

 

x

x

 

x

0.0054

4-SNP

  

x

 

x

x

x

0.0092

  1. + P-values are by Monte-Carlo simulation on 10,000 runs.