Figure 1

LD plot in controls of SNPs in MMPs- 1, 9 and 12. Estimated as r² using Haploview 4.1 output. SNP codes are provided in order of location along each gene; dark grey squares depict strong LD (1.0) with strong confidence, pale grey and white regions represent low LD, and the r² value is provided within each box. SNP positions are demonstrated 5' to 3' relative to contig postion (HuRef NCBI build 36.3).