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Table 4 Genotype distribution according to the presence of LPL HindIII and/or S447X polymorphisms.

From: Additive effects of LPL, APOA5 and APOEvariant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study

Protective variants

Genotypes

TG1

No (N = 916)

H+H+447SS (n = 916)

1.17 (1.13 - 1.22)

One (N = 519)

H+H-447SS (n = 459)

1.11 (1.06 - 1.16)

 

H-H-447SS (n = 56)

 
 

H+H+447SX (n = 4)

 

Two (N = 390)

H+H-447SX (n = 284)

1.00 (0.95 - 1.06)2

 

H-H-447SX (n = 76)

 
 

H-H-447XX (n = 30)

 
  1. H+ represents the most frequent allele of the HindIII variant and H- the least frequent allele. 1Geometric means (mmol/L) and 95% confidence intervals. p < 0.0001 of ANOVA test. 2Significantly different as compared to groups carrying one or no protective variant.
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BMC Medical Genetics

ISSN: 1471-2350

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