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Table 5 Adjusted geometric means (95% confidence intervals) of serum homocysteine (umol/L)*

From: Gene polymorphisms in association with emerging cardiovascular risk markers in adult women

Genotype Minimally adjusted model LSmean (95% CI) Punadjusted PFDR-adjusted Fully adjusted model LSmean (95% CI) Punadjusted PFDR-adjusted
rs1801133 (MTHFR)   0.0002 0.0054   0.0002 0.0052
TT 9.9 (8.9-11.1)    9.8 (8.9-10.8)   
TC 8.2 (8.0-8.5)    8.2 (7.9-8.5)   
CC 7.7 (7.5-8.0)    7.7 (7.6-7.9)   
rs2066470 (MTHFR)   0.05 0.46   0.022 0.28
TT 8.2(7.4-9.1)    8.1 (7.1-9.3)   
TC 7.8 (7.5-8.1)    7.7 (7.5-8.0)   
CC 8.2 (8.0-8.4)    8.2 (8.0-8.4)   
rs1801131 (MTHFR)   0.02 0.28   0.05 0.28
CC 7.9 (7.4-8.4)    8.0 (7.3-8.8)   
CA 7.8 (7.6-8.1)    7.8 (7.5-8.1)   
AA 8.5 (8.1-8.8)    8.4 (8.1-8.7)   
rs1799963 (F2)   0.16 0.85   0.039 0.28
AA -a -   -   
AG 7.7 (7.1-8.4)    7.5 (6.9-8.2)   
GG 8.2 (8.0-8.4)    8.2 (7.9-8.3)   
rs1042713 (ADRB2)   0.17 0.85   0.04 0.28
AA 8.1 (7.7-8.6)    8.1 (7.7-8.5)   
AG 8.4 (8.1-8.7)    8.4 (8.1-8.7)   
GG 7.9 (7.6-8.2)    7.8 (7.5-8.2)   
  1. Note. *Only associations with unadjusted P (i.e., not adjusted for FDR) ≤ 0.05 in fully adjusted models are presented. FDR = false discovery rate. a The frequency is zero for this genotype.