Table 1 Criteria and scoring system for classification of β0-thalassemia/Hb E patients
From: Genetic modifiers of Hb E/β0 thalassemia identified by a two-stage genome-wide association study
Criteria | Status | Score | Status | Score | Status | Score |
|---|---|---|---|---|---|---|
Hb at steady state, g/dL | ≥7.5 | 0 | 6.0--7.5 | 1 | <6 | 2 |
Age at onset, years | >10 | 0 | 2--10 | 0.5 | <2 | 1 |
Age at 1st transfusion, year | >10 | 0 | 4--10 | 1 | <4 | 2 |
Transfusion requirement | Rare/none | 0 | Occasional | 1 | Regular | 2 |
Spleen size, cm | <3 | 0 | 3--10 | 1 | >10 | 2 |
Splenectomy | No | 0 | Yes | 2 |