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Figure 1 | BMC Medical Genetics

Figure 1

From: The molecular basis of beta-thalassemia intermedia in southern China: genotypic heterogeneity and phenotypic diversity

Figure 1

Identification of two novel mutations showing the (A)Term CD+32(A-C) and the (B) Cap+39(C-T). The hematological data and α/β globin genotype of two family members are listed in tables. The probands are labeled by the arrow in the family pedigrees. DNA sequences of sense strand are also shown, downward arrows indicating the mutation nucleotides (overlapping peaks are indicated by N). The alignment of β-globin sequences are shown on the bottom. (EMBL accession No.: chimpanzee ENSPTRT00000006177, human ENST00000335295, horse ENSECAT00000010442, monkey ENSMMUT00000006876, mouse ENSMUST00000098192, and zebrafish ENSDART00000101713). *(Blood samples not avaiable). T+32: Term CD+32(A-C), 27-28:CD 27-28(+C), +39:Cap+39(C-T), and 41-42: CD 41-42 (-CTTT).

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