Skip to main content

Table 2 Haplotypes and phased genotypes distributions for the rs25531 and 5-HTTLPR polymorphisms in the SLC6A4 gene in control and NS-MD populations.

From: Study of the serotonin transporter (SLC6A4) and BDNF genes in French patients with non syndromic mental deficiency

AP2, 5-HTTLPR

Controls

MR patients

MR vs Controls

   

χ 2

p

Haplotypes (5HTT gene)

AL

179 (54.57)

110 (56,12)

0.12

0.73

AS, GL, GS

149 (45.43)

86 (43,88)

  

Phased genotypes (5HTT gene)

AL/AL

45 (27.44)

28 (28.57)

1.28

0.73

AL/AS

73 (44.51)

47 (47.96)

  

AL/GL

16 (9.76)

6 (6.12)

  

AL/GS

0 (0.0)

1 (1.02)

  

Others

30 (18.29)

16 (16.33)

  

Genotypes (5HTT/BDNF genes)

AL AL/Val Val

19 (13.00)

10 (12.66)

0.65

0.88

AL AL/Val Met

21 (14.40)

11 (13.92)

  

Others/Val Val

59 (40.40)

36 (45.57)

  

Others/Val Met

47 (32.20)

22 (27.85)

 Â