Table 5 Estimation of TLR2 haplotype frequencies in the study population by using the expectation-maximization algorithm with the Haploview software
From: Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts
Haplotype | TB patients, N = 184 | Control subjects N = 184 | OR (95% CI) | P value | FDR q value |
|---|---|---|---|---|---|
Counts ratios (frequency %) | Counts ratios (frequency %) | ||||
T-G-(Ins)-T | 97.3/270.7 (26.4) | 113.9/254.1 (31) | 0.8 (0.58-1.1) | 0.166 | 0.573 |
A-A-(Ins)-T | 66.4/301.6 (18) | 75.1/292.9 (20.4) | 0.85 (0.59-1.23) | 0.399 | 0.573 |
A-A-(Del)-C | 37.1/330.9 (10.1) | 46.6/321.4 (12.7) | 0.76 (0.48-1.21) | 0.246 | 0.573 |
A-A-(Del)-T | 38.8/329.2 (10.5) | 42/326 (11.4) | 0.92 (0.58-1.46) | 0.724 | 0.714 |
A-G-(Ins)-T | 50.1/317.9 (13.6) | 27.2/340.8 (7.4) | 1.99 (1.21-3.25) | 0.006 | 0.072 |
T-A-(Ins)-T | 27.7/340.3 (7.5) | 21.4/346.6 (6.3) | 1.36 (0.76-2.44) | 0.301 | 0.573 |
Other** | 7.0/361 (1.9) | 5.9/362.1 (1.6) | 1.17 (0.39-3.52) | 0.78 | 0.714 |