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Table 4 Genotype and allele frequencies of TLR 2 gene polymorphisms in TB patients and control subjects*

From: Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts

Polymorphism

TB patients,

N = 184

Control subjects,

N = 184

OR

(95% CI)

P value

 

N (%)

N (%)

  

-16934 A>T

    

   AA

64 (34.8)

71 (38.6)

 

0.571

   TA

83 (45.1)

73 (39.7)

  

   TT

37 (20.1)

40 (21.7)

  

   A

211 (57.3)

215 (58.4)

  

   T

157 (42.7)

153 (41.6)

1.05 (0.78-1.4)

0.765

-15607 A>G

    

   AA

48 (26.1)

58 (31.5)

 

0.481

   AG

101 (54.9)

91 (49.5)

  

   GG

35 (19)

35 (19)

  

   A

197 (53.5)

207 (55.5)

  

   G

171 (46.5)

161 (44.5)

1.08 (0.81-1.45)

0.592

-196 to -174

Ins>Del

    

Ins/Ins

93 (50.5)

91 (49.5)

 

0.974

   Ins/Del

71 (38.6)

72 (39.1)

  

   Del/Del

20 (10.9)

21 (11.4)

  

   Ins

257(69.8)

254 (69)

  

   Del

111 (30.2)

114 (31)

0.96 (0.7-1.32)

0.81

1350 T>C

    

   TT

131 (71.2)

121 (65.8)

 

0.497

   TC

45 (24.5)

55 (29.9)

  

   CC

8 (4.3)

8 (4.3)

  

   T

307 (83.4)

297 (80.7)

  

   C

61 (16.6)

71 (19.3)

0.83 (0.57-1.21)

0.337

  1. * All p values for Hardy-Weinberg equilibrium in each cohort were > 0.05 except for the one of polymorphism b (-16934A/T) in control cohort (p = 0.005)