MG patients | AA | AG | GG | A | G | MAF | p-vala | Significance threshold | OR (95% C.I.) | p-val referenceb |
---|---|---|---|---|---|---|---|---|---|---|
All patients (n = 446) | 260 | 159 | 27 | 679 | 213 | 0.239 | 0.092 | 0.05 | 0.86 (0.73-1.02) | 0.154 |
Age of onset <40 (n = 226) | 127 | 80 | 19 | 334 | 118 | 0.261 | 0.810 | 6.25 × 10 -3 | 1.03 (0.82-1.28) | 0.032 |
Age of onset >50 (n = 175) | 110 | 59 | 6 | 279 | 71 | 0.203 | 0.010 | 6.25 × 10 -3 | 1.43 (1.09-1.87) | 0.559 |
Ocular (n = 42) | 29 | 12 | 1 | 70 | 14 | 0.167 | 0.040 | 6.25 × 10 -3 | 0.55 (0.31-0.98) | 0.274 |
Generalized (n = 404) | 231 | 147 | 26 | 609 | 199 | 0.246 | 0.240 | 6.25 × 10 -3 | 0.90 (0.76-1.07) | 0.068 |
Not operated (n = 171) | 103 | 58 | 10 | 264 | 78 | 0.228 | 0.124 | 6.25 × 10 -3 | 0.81 (0.63-1.06) | 0.619 |
Normal thymus (n = 60) | 35 | 25 | 0 | 95 | 25 | 0.208 | 0.156 | 6.25 × 10 -3 | 0.72 (0.46-1.13) | 0.833 |
Thymic hyperplasia (n = 157) | 87 | 59 | 11 | 233 | 81 | 0.258 | 0.747 | 6.25 × 10 -3 | 0.96 (0.74-1.25) | 0.090 |
Thymoma (n = 58) | 35 | 17 | 6 | 87 | 29 | 0.250 | 0.695 | 6.25 × 10 -3 | 0.92 (0.60-1.41) | 0.389 |
aControls (n = 1866) | 1015 | 708 | 143 | 2738 | 994 | 0.266 | ||||
bControls (n = 1599) | 989 | 528 | 82 | 2506 | 692 | 0.216 |