Figure 2From: A prevalent mutation with founder effect in Spanish Recessive Dystrophic Epidermolysis Bullosa families Geographic location of alleles carrying the c.6527insC mutation in RDEB patients (red circles). Circle size is proportional to the number of CCGCTCAAA_6527insC alleles. The mutation follows a south-north spatial gradient in the Iberian Peninsula, from Andalusia to Northern Spain. Note that only three alleles that carry the c.6527insC mutation occur in the rest of Europe (blue circles, France, Germany and Portugal)Back to article page