Skip to main content

Table 4 Logistic regression-derived odds ratios (ORs) and 95% confidence intervals (95% CIs) for the risk of myocardial infarction (MI) by eNOS E298D, controlling for demographic and medical history variables among the 422 study participants

From: Association of the eNOS E298D polymorphism and the risk of myocardial infarction in the Greek population

Variable

Category or increment

ORs1(95% CIs)

ORs2(95% CIs)

ORs3(95% CIs)

ORs4(95% CIs)

ORs5(95% CIs)

  

p-value

p-value

p-value

p-value

p-value

eNOS E298D

TT vs. GT+GG

2.06 (1.06-4.00)

2.04 (1.05-3.96)

2.41 (1.18-4.92)

2.57 (1.18-5.60)

2.89 (1.11-7.51)

  

0.032

0.036

0.016

0.018

0.029

Age

60+ vs. < 60 years

 

1.11 (0.75-1.65)

1.76 (1.13-2.75)

2.24 (1.38-3.64)

1.00 (0.54-1.80)

   

0.602

0.013

0.001

0.969

Gender

female vs. male

 

0.86 (0.48-1.53)

1.26 (0.67-2.37)

1.19 (0.62-2.30)

1.37 (0.66-2.87)

   

0.606

0.470

0.608

0.401

BMI

2 kg/m2 more

  

1.14 (1.00-1.30)

1.13 (0.98-1.30)

1.12 (0.97-1.30)

    

0.057

0.096

0.132

Smoking

yes vs. no

  

4.93 (2.98-8.15)

5.53 (3.21-9.54)

6.83 (3.64-12.84)

    

< 0.0001

< 0.0001

< 0.0001

Family history of CAD

yes vs. no

   

6.97 (3.98-12.21)

6.91 (3.69-12.94)

     

< 0.0001

< 0.0001

Hypertension

yes vs. no

    

11.91 (6.70-21.17)

      

< 0.0001

  1. 1 = Model 1: Unadjusted odds ratio for eNOS E298D
  2. 2 = Model 2: Odds ratio for mutually adjusted eNOS E298D, age and gender
  3. 3 = Model 3: Odds ratio for mutually adjusted eNOS E298D, age, gender, BMI and smoking
  4. 4 = Model 4: Odds ratio for mutually adjusted eNOS E298D, age, gender, BMI, smoking and family history of CAD
  5. 5 = Model 5: Odds ratio for mutually adjusted eNOS E298D, age, gender, BMI, smoking, family history of CAD and hypertension