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Table 1 Participant demographics and genotype distributions

From: The G-Protein β3 subunit 825 TT genotype is associated with epigastric pain syndrome-like dyspepsia

 

Controls

(n = 761)

FD, total

(n = 68)

P 2

EPS

(n = 43)4

P 2

PDS

(n = 40)4

P 2

Age (years)1

45 (19-83)

43 (23-69)

0.164

43 (23-69)

0.079

43 (23-64)

0.053

Sex (male%)

42.7

36.8

0.372

39.5

0.752

32.5

0.251

Smoking (%)

27.6

27.9

1.000

34.9

0.299

27.5

1.000

Drinking (%)

30.0

36.8

0.272

37.2

0.314

32.5

0.726

BMI (kg/m2)1

22.0

(15.6-37.1)

21.5

(17.4-29.3)

0.400

21.6

(17.4-29.3)

0.801

20.9

(17.4-29.3)

0.084

ALT (IU/L)1

18 (4-40)

17 (8-38)

0.478

18 (8-38)

0.965

17 (9-32)

0.189

Blood pressure (mmHg)1

       

   Systolic

118

(78-223)

117

(78-175)

0.735

116

(95-164)

0.994

115

(78-175)

0.282

   diastolic

72

(42-126)

72

(48-104)

0.714

72

(49-104)

0.895

68

(48-104)

0.259

GNB3 genotype (%)

       

   CC (wild type)

25.1

25.0

 

18.6

 

25.0

 

   CT

48.4

42.6

 

39.5

 

42.6

 

   TT

26.5

32.4

0.546

41.9

0.113

32.4

0.546

   P for HWE3

0.368

0.240

 

0.282

 

0.240

 
  1. 1Data are shown as median (range).
  2. 2 P vs. controls by Mann-Whitney U-test (for age, BMI, ALT, and blood pressure) or Fisher's exact test (for other variables).
  3. 3 P for deviation from Hardy-Weinberg equilibrium (HWE).
  4. 4Fifteen subjects simultaneously had EPS- and PDS-like symptoms.
  5. FD, functional dyspepsia; EPS, epigastric pain syndrome; PDS, postprandial distress syndrome; BMI, body mass index.