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Table 1 Characteristics of the investigated samples of the patients with PCOS (means and standard deviations or percent).

From: Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)

variables

386 patients with PCOS

age [years]

28.0 ± 6.5

body weight [kg]

88.3 ± 25.8

BMI [kg/m2]

31.4 ± 8.7

waist [cm]

98.8 ± 62.4

eumenorrhea [%]

8.7

oligomenorrhea [%]

65.7

amenorrhea [%]

25.5

hirsutism-Score [F/G]

8.9 ± 6.6

hirsutism [%]

54.0

acne [%]

47.8

alopecia [%]

27.3

PCO [%]

82.8

HA + OA [%]

92.3

   HA + OA with PCO [%]

57.5

   HA + OA without PCO [%]

12.2

   HA + OA, PCO unknown [%]

30.3

HA + PCO [%]

5.2

OA + PCO [%]

2.5

testosterone [nmol/l]

2.8 ± 2.8

FAI

20.3 ± 83.9

bioavailable testosterone [ng/ml]

0.4 ± 0.8

HOMA-IR [μmol/lxmmol/l2]

3.7 ± 3.3

AUCI [mUxh/l]

262.6 ± 184.1

FTO (rs9939609; MAF A allele)

46.2

INSIG2 (rs7566605; MAF C allele)

33.8

TCF7L2 (rs7903146; MAF T allele)

28.4

MC4R (rs2229616; MAF T allele)

1.6

MC4R (rs17782313; MAF C allele)

29.0

MC4R (rs12970134; MAF A allele)

31.7

  1. BMI = body mass index; F/G = hirsutism-score by Ferriman/Gallwey; FAI = free androgen index; PCO = polycystic ovary; HA = hyperandrogenism; OA = oligo-/amenorrhea; HOMA-IR = homeostasis model assessment for insulin resistance; AUCI = area under the curve of insulin response; MAF = minor allele frequency