A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population

Table 2 Association analysis of GIP SNPs with Type 2 Diabetes

	rs2291725	rs2291726
Major allele	A	G
Minor allele	G	A
Controls
n	998	1000
Major homozygous	325	297
Hetrozygous	481	472
Minor homozygous	192	231
Major allele frequency	0.57	0.53
Minor allele frequency	0.43	0.47
HWE (P -value)	0.555	0.100
Cases (T2DM)
n	989	1000
Major homozygous	326	283
Hetrozygous	458	501
Minor homozygous	205	216
Major allele frequency	0.56	0.53
Minor allele frequency	0.44	0.47
HWE (P -value)	0.060	0.837
Tests for association (C.I.: 95% confidence interval)
Odds ratio	1.022	0.998
Allele frequency	0.728	0.974
Dominant model	0.850	0.490
Recessive model	0.406	0.421

ISSN: 1471-2350