Genomewide association study for onset age in Parkinson disease

BMC Medical Genetics

Table 2 Location and minor allele frequency (MAF) information for 24 SNPs selected for replication study in Italian sample

Chr	SNP	SNP position^a	Minor Allele	MAF	Genes in Region^b
1	rs7556447	2,335,959	G	0.24	PEX10
1	rs1355637^c	148,849,062	T	0.19	MCL1\|ENSA
1	rs10918270	160,182,125	A	0.41	ATF6
2	rs11899121	20,231,454	C	0.50	SDC1
2	rs7577851^c	69,577,214	T	0.17	AAK1
2	rs17817190	134,068,118	G	0.11	NAP5
6	rs6936388	42,275,464	T	0.25	CCND3\|TAF8\|GUCA1A\|GUCA1B\|MRPS10
6	rs1572662	154,853,289	A	0.36	CNKSR3\|CLDN20\|RBM16\|TIAM2\|TFB1M
7	rs1420143^c	29,514,849	C	0.44	CHN2
7	rs17663983	76,243,177	T	0.12
10	rs12261736	52,738,610	T	0.28	PRKG1
10	rs7076519	127,738,829	C	0.33	ADAM12
11	rs10767971^c	32,852,240	T	0.42	PRRG4\|QSER1
12	rs12829697	30,067,223	G	0.13
12	rs10773917	130,572,784	T	0.23
13	rs4771006^d	26,180,684	A	0.49	WASF3
13	rs676495^c	29,561,754	T	0.24
14	rs10147486	47,054,769	T	0.27	MDGA2
15	rs17565841	25,670,842	A	0.10	OCA2
17	rs9904572	12,803,084	A	0.34	RICH2
17	rs4791571^c	14,155,801	A	0.42	HS3ST3B1
18	rs1941184	27,292,121	C	0.30	DSG3
19	rs10420134	40,953,768	G	0.18	C19orf55\|SNX26
20	rs3887942	23,925,072	G	0.19	GGTLC1

^a From NCBI Build 36 reference; ^b Nearest genes within 100 kb of SNP;^c SNP was genotyped in Mayo-Perlegen LEAPS GWAS;^d SNP was genotyped in GenePD-PROGENI GWAS

ISSN: 1471-2350