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Table 2 Associations of representative SNPs in the UCP2-UCP3 gene region with indices of abdominal obesity at the baseline

From: Variation in the UCP2 and UCP3genes associates with abdominal obesity and serum lipids: The Finnish Diabetes Prevention Study

  

Genotype

  

SNP

Obesity index

Homozygous for the common allele

Heterozygous

Homozygous for the rare allele

p a

q

rs659366

WC, cm

102 ± 11

101 ± 11

100 ± 11

0.033

0.010

 

WHR

0.93 ± 0.07

0.92 ± 0.07

0.91 ± 0.08

0.048

0.014

 

WHtR

0.61 ± 0.06

0.61 ± 0.06

0.61 ± 0.07

0.119

0.027

rs653529

WC, cm

102 ± 11

101 ± 11

100 ± 11

0.011

0.007

 

WHR

0.93 ± 0.07

0.92 ± 0.07

0.91 ± 0.08

0.009

0.006

 

WHtR

0.61 ± 0.06

0.61 ± 0.06

0.60 ± 0.07

0.022

0.010

rs15763

WC, cm

102 ± 11

100 ± 10

100 ± 12

0.075

0.019

 

WHR

0.92 ± 0.07

0.92 ± 0.07

0.90 ± 0.07

0.018

0.010

 

WHtR

0.61 ± 0.07

0.60 ± 0.06

0.60 ± 0.07

0.024

0.010

rs1726745

WC, cm

100 ± 11

102 ± 11

102 ± 11

0.008

0.006

 

WHR

0.91 ± 0.08

0.92 ± 0.07

0.93 ± 0.07

0.031

0.010

 

WHtR

0.60 ± 0.06

0.62 ± 0.06

0.61 ± 0.07

0.003

0.006

  1. Data are means ± SD
  2. aUnivariate ANOVA, adjusted for age, gender, BMI
  3. WC, waist circumference; WHR, waist-to-hip ratio; WHtR, waist-to-height ratio