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Table 1 Statistical analysis of HECTD2 marker rs12249854

From: HECTD2, a candidate susceptibility gene for Alzheimer's disease on 10q

rs12249854

AD n (%)

Controls n (%)

P-value

(Chi-square)

P-value

(PLINK)

AA

2 (0.6)

0 (0.0)

0.0648

0.051

TA

33 (10.3)

47 (7.8)

  

TT

285 (89.1)

554 (92.2)

  

A

37 (5.8)

47 (3.9)

0.0668

0.079

T

603 (94.2)

1155 (96.1)

  
  1. P-values were calculated using a chi-squared test and as an alternative we also implemented 1,000,000 permutations using PLINK [36]. http://pngu.mgh.harvard.edu/purcell/plink/