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Table 4 Association of PCK1 haplotypes with type 2 diabetes among UK-resident South Asians

From: The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

LD Block

Haplotype

SNP1

SNP2

SNP3

SNP4

Diabetic subjects Fa

Control subjects Fa

Odds ratio (OR)

p

1

Haplotype 1

G

C

-

-

0.472

0.427

1.20

0.024

1

Haplotype 2

C

C

-

-

0.341

0.369

0.89

0.150

1

Haplotype 3

C

T

-

-

0.185

0.204

0.89

0.239

2

Haplotype 4

-

-

C

T

0.405

0.417

0.95

0.538

2

Haplotype 5

-

-

C

C

0.311

0.297

1.06

0.475

2

Haplotype 6

-

-

T

C

0.271

0.264

1.03

0.710

2

Haplotype 7

-

-

T

T

0.014

0.021

0.63

0.130

  1. aF = Haplotype frequency. All values were calculated using the full dataset, the minimum age of control subjects being 35 years. SNP1 = rs2071023, SNP2 = rs6070157, SNP3 = rs2070756, SNP4 = rs2179706.