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Figure 1 | BMC Medical Genetics

Figure 1

From: Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced β-cell function in non-diabetic subjects

Figure 1

Fifty-five-kb genomic region of human chromosome 9q22 harbouring the NR4A3 gene and HapMap LD data of the 17 common (minor allele frequency ≥ 0.05) informative SNPs within this region. The NR4A3 gene consists of eight exons and seven introns and spans 45 kb from nucleotide 101,623,958 to nucleotide 101,668,994. The locations of the five tagging SNPs rs7047636, rs1526267, rs2416879, rs12686676, and rs10819699 are indicated by black arrows. The Haploview LD colour scheme 'R-squared' was chosen to visualize regions of high linkage disequilibrium (black diamonds: complete LD; dark grey diamonds: strong LD; light grey diamonds: weak LD). Within the diamonds, the r2 values are given (black diamonds: r2 = 1.0). LD – linkage disequilibrium; SNP – single nucleotide polymorphism.

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BMC Medical Genetics

ISSN: 1471-2350

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