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Figure 1 | BMC Medical Genetics

Figure 1

From: Novel quantitative trait locus is mapped to chromosome 12p11 for left ventricular mass in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis

Figure 1

Multipoint linkage plots for left ventricular mass on chromosome 12 in overall families and subset families defined by ordered-subset analysis on waist circumference. Maximum multipoint LOD scores were plotted along the chromosomal position in centimorgans (cM) on chromosome 12. Horizontal lines indicate the one-LOD unit down supporting intervals. All 100 families were used in the overall analysis and the LOD score is depicted by solid line. In the ordered-subset analysis, the families were ranked by mean waist circumference from high to low and sequentially introduced to linkage analysis until the maximum LOD score was achieved. 54 families with the highest waist circumference were used in the final analysis and the LOD score is depicted by the dashed line.

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