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Table 5 Postnatal characteristics at 6, 12, and 24 months according to TCF7L2 rs7903146 genotype.

From: Type 2 diabetes gene TCF7L2polymorphism is not associated with fetal and postnatal growth in two birth cohort studies

Generation R

Ā 

CC

(n = 1375)

CT

(n = 1063)

TT

(n = 237)

p-value#

6 months

Head circumference (SDS)

-0.02 (0.93)

-0.03 (0.89)

-0.06 (0.91)

0.83

n = 2675

Height (SDS)

0.03 (0.91)

0.03 (0.90)

0.07 (0.93)

0.81

Ā 

Weight (SDS)

0.41 (0.96)

0.44 (0.95)

0.54 (0.99)

0.14

12 months

Head circumference (SDS)

0.00 (0.89)

-0.04 (0.94)

-0.03 (1.12)

0.54

n = 2559

Height (SDS)

-0.01 (0.90)

-0.05 (0.90)

-0.01 (0.90)

0.70

Ā 

Weight (SDS)

0.18 (0.98)

0.18 (0.99)

0.24 (1.00)

0.63

24 months

Height (SDS)

-0.19 (0.93)

-0.21 (0.89)

-0.18 (0.87)

0.82

n = 2445

Weight (SDS)

-0.11 (0.99)

-0.13 (1.00)

-0.09 (0.96)

0.87

SGA cohort

Ā 

CC

(n = 143)

CT

(n = 107)

TT

(n = 22)

Ā 

6 months

Head circumference (SDS)

-1.38 (0.92)

-1.36 (0.90)

-1.74 (1.04)

0.41

n = 272

Height (SDS)

-2.39 (1.37)

-2.43 (1.26)

-2.51 (1.55)

0.93

Ā 

Weight (SDS)

-2.18 (1.40)

-2.22 (1.26)

-2.37 (2.05)

0.86

12 months

Head circumference (SDS)

-1.21 (0.83)

-1.24 (0.88)

-1.72 (1.06)

0.16

n = 268

Height (SDS)

-2.25 (1.25)

-2.30 (1.06)

-2.30 (1.47)

0.94

Ā 

Weight (SDS)

-2.14 (1.41)

-2.25 (1.15)

-2.17 (1.89)

0.82

24 months

Head circumference (SDS)

-1.10 (0.82)

-1.13 (0.87)

-1.60 (1.06)

0.20

n = 244

Height (SDS)

-2.39 (1.24)

-2.47 (1.05)

-2.94 (1.04)

0.20

Ā 

Weight (SDS)

-2.19 (1.33)

-2.31 (1.21)

-3.06 (1.65)

0.04

  1. Values expressed as mean (SD). SDS = standard deviation score for age and gender.
  2. # p-values for additive models. Differences were tested using linear regression.