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Table 5 Postnatal characteristics at 6, 12, and 24 months according to TCF7L2 rs7903146 genotype.

From: Type 2 diabetes gene TCF7L2polymorphism is not associated with fetal and postnatal growth in two birth cohort studies

Generation R   CC (n = 1375) CT (n = 1063) TT (n = 237) p-value#
6 months Head circumference (SDS) -0.02 (0.93) -0.03 (0.89) -0.06 (0.91) 0.83
n = 2675 Height (SDS) 0.03 (0.91) 0.03 (0.90) 0.07 (0.93) 0.81
  Weight (SDS) 0.41 (0.96) 0.44 (0.95) 0.54 (0.99) 0.14
12 months Head circumference (SDS) 0.00 (0.89) -0.04 (0.94) -0.03 (1.12) 0.54
n = 2559 Height (SDS) -0.01 (0.90) -0.05 (0.90) -0.01 (0.90) 0.70
  Weight (SDS) 0.18 (0.98) 0.18 (0.99) 0.24 (1.00) 0.63
24 months Height (SDS) -0.19 (0.93) -0.21 (0.89) -0.18 (0.87) 0.82
n = 2445 Weight (SDS) -0.11 (0.99) -0.13 (1.00) -0.09 (0.96) 0.87
SGA cohort   CC (n = 143) CT (n = 107) TT (n = 22)  
6 months Head circumference (SDS) -1.38 (0.92) -1.36 (0.90) -1.74 (1.04) 0.41
n = 272 Height (SDS) -2.39 (1.37) -2.43 (1.26) -2.51 (1.55) 0.93
  Weight (SDS) -2.18 (1.40) -2.22 (1.26) -2.37 (2.05) 0.86
12 months Head circumference (SDS) -1.21 (0.83) -1.24 (0.88) -1.72 (1.06) 0.16
n = 268 Height (SDS) -2.25 (1.25) -2.30 (1.06) -2.30 (1.47) 0.94
  Weight (SDS) -2.14 (1.41) -2.25 (1.15) -2.17 (1.89) 0.82
24 months Head circumference (SDS) -1.10 (0.82) -1.13 (0.87) -1.60 (1.06) 0.20
n = 244 Height (SDS) -2.39 (1.24) -2.47 (1.05) -2.94 (1.04) 0.20
  Weight (SDS) -2.19 (1.33) -2.31 (1.21) -3.06 (1.65) 0.04
  1. Values expressed as mean (SD). SDS = standard deviation score for age and gender.
  2. # p-values for additive models. Differences were tested using linear regression.