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Table 4 Birth characteristics in both cohorts according to TCF7L2 rs7903146 genotype of child.

From: Type 2 diabetes gene TCF7L2polymorphism is not associated with fetal and postnatal growth in two birth cohort studies

Generation R   CC (n = 1762) CT (n = 1351) TT (n = 306) p-value#
Gestational age (weeks) n = 3419 40.3 (36.7 – 42.3) 40.3 (36.6 – 42.4) 40.1 (37.1 – 42.6) 0.83
Birth head circumference (SDS)* n = 2314 0.22 (0.9) 0.24 (0.9) 0.26 (0.9) 0.55
Birth length (SDS)* n = 1959 -0.07 (1.0) -0.08 (1.0) 0.00 (1.1) 0.66
Birth weight (SDS) n = 3419 0.21 (1.0) 0.22 (1.0) 0.20 (1.0) 0.97
SGA Cohort   CC (n = 270) CT (n = 255) TT (n = 41) p-value #
Gestational age (weeks) n = 566 38.0 (28.6 – 42.0) 38.0 (28.6 – 41.0) 38.0 (29.0 – 42.0) 0.57
Birth head circumference (SDS) n = 203 -1.51 (1.4) -1.20 (1.6) -1.31 (1.4) 0.32
Birth length (SDS) n = 491 -3.11 (1.4) -3.27 (1.5) -3.02 (1.5) 0.41
Birth weight (SDS) n = 566 -2.40 (1.0) -2.46 (0.9) -2.32 (0.9) 0.58
  1. * Length and head circumference were measured in the first two months of after birth.
  2. Values are means (SD) or medians (95% range). SDS = standard deviation score for age and gender.
  3. # p-values for additive models. Differences were tested using linear regression analyses.