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Table 3 Fetal characteristics according to fetal TCF7L2 rs7903146 genotype in the Generation R study.

From: Type 2 diabetes gene TCF7L2polymorphism is not associated with fetal and postnatal growth in two birth cohort studies

Ā 

CC

(n = 1736)

CT

(n = 1329)

TT

(n = 301)

p-value#

Fetal characteristics second trimester

Ā Ā Ā Ā 

ā€ƒā€ƒā€ƒHead circumference (SDS)

0.04 (1.0)

0.02 (1.0)

0.05 (0.9)

0.88

ā€ƒā€ƒā€ƒFemur length (SDS)

-0.01 (1.0)

-0.01 (1.0)

0.05 (0.9)

0.64

ā€ƒā€ƒā€ƒEstimated fetal weight (SDS)

-0.06 (1.0)

-0.07 (1.0)

0.00 (1.0)

0.57

Fetal characteristics third trimester

Ā Ā Ā Ā 

ā€ƒā€ƒā€ƒHead circumference (SDS)

0.11 (1.0)

0.13 (1.0)

0.15 (0.9)

0.45

ā€ƒā€ƒā€ƒFemur length (SDS)

0.01 (1.0)

-0.02 (1.0)

-0.04 (1.0)

0.34

ā€ƒā€ƒā€ƒEstimated fetal weight (SDS)

0.12 (1.0)

0.14 (1.0)

0.11 (0.9)

0.99

  1. Values are means (SD). SDS = standard deviation score for age and gender.
  2. # p-values for additive models. Differences were tested using linear regression analyses.