From: An Open Access Database of Genome-wide Association Results
 | Including WTCCC/DGI results (n = 5966 genes) | Excluding WTCCC/DGI results (n = 2888 genes) | ||||
---|---|---|---|---|---|---|
Gene Ontology category | RefSeq genes in Category | RefSeq genes observed in GWAS | GO category enrichment | P-value for enrichment | FDR | P-value for enrichment |
GO:0007155_cell_adhesion | 650 | 309 | 1.41 | 4.56E-14 | 0 | 1.99E-17 |
GO:0051056_regulation_of_small_GTPase_mediated_signal_transduction | 161 | 94 | 1.73 | 9.73E-11 | 0 | 3.76E-06 |
GO:0051179_localization | 2493 | 975 | 1.16 | 1.12E-10 | 0 | 2.32E-07 |
GO:0006810_transport | 2128 | 837 | 1.17 | 1.13E-09 | 0 | 2.46E-06 |
GO:0051234_establishment_of_localization | 2189 | 856 | 1.16 | 2.64E-09 | 0 | 2.92E-06 |
GO:0006811_ion_transport | 682 | 297 | 1.29 | 2.39E-08 | 0 | 1.32E-08 |
GO:0009966_regulation_of_signal_transduction | 408 | 189 | 1.37 | 5.37E-08 | 0 | 0.00132 |
GO:0046578_regulation_of_Ras_protein_signal_transduction | 122 | 70 | 1.70 | 6.27E-08 | 0 | 0.00014 |
GO:0007156_homophilic_cell_adhesion | 134 | 75 | 1.66 | 8.92E-08 | 0 | 6.35E-09 |
GO:0016337_cell-cell_adhesion | 245 | 121 | 1.46 | 2.26E-07 | 0.000091 | 1.04E-07 |
GO:0006468_protein_amino_acid_phosphorylation | 536 | 236 | 1.31 | 2.43E-07 | 0.000083 | 7.42E-07 |
GO:0043687_post-translational_protein_modification | 1171 | 473 | 1.20 | 2.83E-07 | 0.000154 | 0.00097 |
GO:0007265_Ras_protein_signal_transduction | 177 | 92 | 1.54 | 3.59E-07 | 0.000143 | 0.00013 |
GO:0006464_protein_modification_process | 1399 | 555 | 1.18 | 3.91E-07 | 0.0002 | 0.00721 |
GO:0007242_intracellular_signaling_cascade | 1210 | 486 | 1.19 | 4.26E-07 | 0.000188 | 0.00040 |
GO:0006817_phosphate_transport | 83 | 50 | 1.79 | 6.31E-07 | 0.000176 | 2.10E-05 |