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Table 2 Allele frequenciesa of the IL18R1 and IL18RAP SNPs in the MORGAM cohorts

From: Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project

  

FINRISK

N = 1176

ATBC

N = 1270

Sweden

N = 195

PRIME/N.Ireland

N = 251

PRIME/France

N = 296

Gene

SNP

Non-cases

N = 609

Casesb

N = 567

Non-cases

N = 718

Cases

N = 552

Non-cases

N = 128

Cases

N = 67

Non-cases

N = 135

Cases

N = 116

Non-cases

N = 182

Cases

N = 114

IL18R1

rs1420098 (T/C)

0.37

0.38

0.39

0.41

0.43

0.41

0.42

0.42

0.41

0.37

 

rs1420096 (T/C)

0.46

0.47

0.46

0.47

0.52

0.43

0.50

0.48

0.55

0.53

 

rs11465656 (I/D)

0.04

0.04

0.04

0.04

0.03

0.02

0.04

0.06

0.05

0.03

 

rs3732127 (G/C)

0.21

0.18

0.17

0.17

0.14

0.22*

0.17

0.19

0.19

0.16

 

rs11465660 C/A)

0.10

0.10

0.12

0.12

0.13

0.13

0.11

0.07

0.07

0.07

IL18RAP

rs11465670 (T/C)

0.09

0.09

0.11

0.12

0.11

0.16

0.13

0.15

0.13

0.13

 

rs4851581 (A/G)

0.14

0.15

0.15

0.13

0.08

0.03

0.08

0.10

0.09

0.11

 

rs1420106 (G/A)

0.18

0.20

0.20

0.19

0.21

0.19

0.20

0.18

0.22

0.28

 

rs1420105 (C/T)

0.46

0.46

0.46

0.47

0.51

0.43

0.50

0.48

0.53

0.53

 

rs11465673 (T/C)

0.09

0.10

0.12

0.12

0.13

0.14

0.11

0.07

0.07

0.06

 

rs11465702 (A/G)

0.19

0.16*

0.15

0.14

0.12

0.16

0.14

0.14

0.13

0.11

  1. a Allele frequency of the minor allele.
  2. b Cases: CHD and strokes were combined
  3. *: Significant cases/non-cases comparison at p < 0.05