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Table 2 Allele frequenciesa of the IL18R1 and IL18RAP SNPs in the MORGAM cohorts

From: Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project

   FINRISK N = 1176 ATBC N = 1270 Sweden N = 195 PRIME/N.Ireland N = 251 PRIME/France N = 296
Gene SNP Non-cases N = 609 Casesb N = 567 Non-cases N = 718 Cases N = 552 Non-cases N = 128 Cases N = 67 Non-cases N = 135 Cases N = 116 Non-cases N = 182 Cases N = 114
IL18R1 rs1420098 (T/C) 0.37 0.38 0.39 0.41 0.43 0.41 0.42 0.42 0.41 0.37
  rs1420096 (T/C) 0.46 0.47 0.46 0.47 0.52 0.43 0.50 0.48 0.55 0.53
  rs11465656 (I/D) 0.04 0.04 0.04 0.04 0.03 0.02 0.04 0.06 0.05 0.03
  rs3732127 (G/C) 0.21 0.18 0.17 0.17 0.14 0.22* 0.17 0.19 0.19 0.16
  rs11465660 C/A) 0.10 0.10 0.12 0.12 0.13 0.13 0.11 0.07 0.07 0.07
IL18RAP rs11465670 (T/C) 0.09 0.09 0.11 0.12 0.11 0.16 0.13 0.15 0.13 0.13
  rs4851581 (A/G) 0.14 0.15 0.15 0.13 0.08 0.03 0.08 0.10 0.09 0.11
  rs1420106 (G/A) 0.18 0.20 0.20 0.19 0.21 0.19 0.20 0.18 0.22 0.28
  rs1420105 (C/T) 0.46 0.46 0.46 0.47 0.51 0.43 0.50 0.48 0.53 0.53
  rs11465673 (T/C) 0.09 0.10 0.12 0.12 0.13 0.14 0.11 0.07 0.07 0.06
  rs11465702 (A/G) 0.19 0.16* 0.15 0.14 0.12 0.16 0.14 0.14 0.13 0.11
  1. a Allele frequency of the minor allele.
  2. b Cases: CHD and strokes were combined
  3. *: Significant cases/non-cases comparison at p < 0.05