Skip to main content
Figure 3 | BMC Medical Genetics

Figure 3

From: Prevalence of pathogenetic MC4R mutations in Italian children with early Onset obesity, tall stature and familial history of obesity

Figure 3

Functional Agonist Data. Illustration of the activity of α-MSH, ACTH1–24, β-MSH, γ2-MSH, and synthetic agonist JRH887–9 at the wild type MC4R, Q307X MC4R and Y332H MC4R. Agonists did not evocate any response by binding the Q307X MC4R. When the agonists were binding the Y332H MC4R the evocated response was similar to that observed for the wild type.

Back to article page