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Table 6 Association of IL6 haplotypes with COPD and ln(CRP)

From: IL6 and CRPhaplotypes are associated with COPD risk and systemic inflammation: a case-control study

 

COPD *

Ln (CRP) †

Haplotype

OR (95%CI)

P-value

Coefficient ± SE

P-value

H1

0.92 (0.56–1.51)

0.75

0.005 ± 0.17

0.98

H2

4.82 (1.64–4.18)

0.004

-0.94 ± 0.27

0.0005

H3

1.71 (0.85–3.44)

0.13

-0.12 ± 0.21

0.54

H4

REFERENT

REFERENT

H5

1.01 (0.64–1.60)

0.95

0.01 ± 0.17

0.93

H6

0.93 (0.51–1.67)

0.80

-0.36 ± 0.22

0.10

H7

0.71 (0.37–1.36)

0.3

-0.02 ± 0.24

0.94

Others‡

1.48 (0.79–2.78)

0.22

-0.07 ± 0.20

0.73

  1. * Logistic regression analyses were adjusted for age, sex and tobacco consumption (pack-years smoked).
  2. † Linear regression analyses were adjusted for age, sex, BMI and 6MWD.
  3. ‡ Rare haplotypes (frequency < 2.5%) were coded in aggregate as "others"